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Diflunisal

Basic Information

  • CAS No.: 22494-42-4
  • Purity: 99%
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Quality products?make an important contribution to long-term revenue and profitability. Factory sells Diflunisal 22494-42-4 with sufficient production capacity

1.What is the Diflunisal ?

Diflunisal acts as an analgesic agent, used in Alzheimer’s studies (1,2,3) as an anti-inflammatory. As well as in autolytic regulation of human kallikrein -related peptidase 6 (4).

[Co(2,2'-bipyridine)<sub>2</sub>(diflunisal)][hexafluorophosphate]

[Co(2,2'-bipyridine)2 (diflunisal)][hexafluorophosphate]

[2,2]bipyridinyl
366-18-7

[2,2]bipyridinyl

2',4'-difluoro-4-hydroxybiphenyl-3-carboxylic acid
22494-42-4

2',4'-difluoro-4-hydroxybiphenyl-3-carboxylic acid

Conditions
Conditions Yield
With ascorbic acid; In aq. phosphate buffer; at 37 ℃; for 24h; Time;
[Co(1,10-phenanthroline)<sub>2</sub>(diflunisal)][hexafluorophosphate]

[Co(1,10-phenanthroline)2 (diflunisal)][hexafluorophosphate]

1,10-Phenanthroline
66-71-7

1,10-Phenanthroline

2',4'-difluoro-4-hydroxybiphenyl-3-carboxylic acid
22494-42-4

2',4'-difluoro-4-hydroxybiphenyl-3-carboxylic acid

Conditions
Conditions Yield
With ascorbic acid; In aq. phosphate buffer; at 37 ℃; for 24h; Time; Reagent/catalyst;

2.What is the CAS number for Diflunisal ?

The CAS number of Diflunisal is 22494-42-4.

More information of Diflunisal 22494-42-4 are:

CAS?Number

22494-42-4

Density

1.437 g/cm3

Melting Point

207-209 °C

Boiling Point

386.9 °C at 760 mmHg

Flash Point

187.8 °C

Vapor Pressure

2.75E-07mmHg at 25°C

Refractive Index

1.601

HS CODE

2918290000

PSA

57.53000

LogP

3.03560

Pka

pKa 3.3 (H2O I=0.1) (Uncertain)

3.What are another words for Diflunisal ?

Synonyms?for?Diflunisal 22494-42-4:3-Biphenylcarboxylicacid, 2',4'-difluoro-4-hydroxy- (8CI);2',4'-Difluoro-4-hydroxybiphenyl-3-carboxylicacid;5-(2,4-Difluorophenyl)salicylic acid;Adomal;Difludol;Diflunisal;Diflusinal;Dolisal;Doloban;Dolobid;Dolobis;Flovacil;Fluniget;Fluodonil;Flustar;MK 647;

4.What is the molecular formula of Diflunisal?

The chemical formula of ?Diflunisal is?C13H8F2O3 which containing 13 Carbon atoms,8 Hydrogen atoms,2 Fluorine atoms and 3 Oxygen atoms,and the molecular weight of??Diflunisal?is 250.202.

5.What is Diflunisal (22494-42-4) used for?

Diflunisal is a non-steroidal anti-inflammatory drug (NSAID) that inhibits both COX-1 (IC50 = 113 μM) and COX-2 (IC50s = 8.2 and 134 μM for human whole blood assay and human-modified whole blood assays, respectively). Peak plasma levels are achieved within two hours, with little metabolism before excretion in the urine. The terminal plasma half-life is approximately eight hours.

InChI:InChI=1/C13H8F2O3/c14-10-3-1-8(6-11(10)15)7-2-4-12(16)9(5-7)13(17)18/h1-6,16H,(H,17,18)

Relevant articles related to Diflunisal:

Article

Source

Electron-Poor, Fluoro-Containing Arylboronic Acids as Efficient Coupling Partners for Bis(1,5-cyclooctadiene)nickel(0)/Tricyclohexylphosphine-Catalyzed Cross-Coupling Reactions of Aryl Arenesulfonates

Chen, Wen-Bo,Xing, Chun-Hui,Dong, Jie,Hu, Qiao-Sheng

, p. 2072 - 2076 (2016)

Nickel- and Palladium-Catalyzed Cross-Coupling of Stibines with Organic Halides: Site-Selective Sequential Reactions with Polyhalogenated Arenes

Ghaderi, Arash,Kambe, Nobuaki,Le, Liyuan,Lu, Hao,Qiu, Renhua,Tang, Ting,Tong, Zhou,Wong, Wai-Yeung,Xu, Zhi,Yin, Shuang-Feng,Zeng, Dishu,Zhang, Dejiang,Zhang, Zhao

, p. 854 - 867 (2022/01/19)

6.Buy Diflunisal with the best price .

Hangzhou innopharma technology Co,.Ltd. is a quality supplier of Diflunisal. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Diflunisal 22494-42-4.

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