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3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol
Basic Information
- CAS No.: 207679-81-0
- Purity: 99%
Details
Quality products?make an important contribution to long-term revenue and profitability. Factory supply good quality 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0 with stock
1.What is the 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol ?
A metabolite of Tolterodine, a muscarinic receptor antagonist used in the treatment of urinary incontinence.
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-
214601-16-8
(R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester
-
-
207679-81-0
(R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol
| Conditions | Yield |
|---|---|
|
(R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester;
With
sodium hydroxide;
In
methanol;
at 0 - 35 ℃;
Inert atmosphere;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 5 - 25 ℃;
for 4h;
With
water; sodium hydroxide;
In
tetrahydrofuran;
at 0 - 5 ℃;
for 3h;
|
98%
|
|
(R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester;
With
sodium hydroxide;
In
methanol;
at 0 - 35 ℃;
Inert atmosphere;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 5 - 25 ℃;
With
water; sodium hydroxide;
In
tetrahydrofuran;
for 3h;
|
98%
|
|
(R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 20 ℃;
for 3.5h;
With
ammonium chloride;
In
tetrahydrofuran;
at -10 ℃;
|
95%
|
|
With
sodium bis(2-methoxyethoxy)aluminium dihydride;
In
tetrahydrofuran;
at 0 - 5 ℃;
for 2h;
Inert atmosphere;
|
-
-
156755-37-2
{4-(benzyloxy)-3-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]phenyl}methanol
-
-
207679-81-0
(R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol
| Conditions | Yield |
|---|---|
|
With
hydrogen;
5% Pd(II)/C(eggshell);
In
methanol;
at 50 - 55 ℃;
|
98%
|
|
With
hydrogen;
nickel;
In
methanol;
at 20 ℃;
for 4 - 5h;
|
96.5%
|
|
With
hydrogen;
In
methanol;
under 3000.3 - 3750.38 Torr;
|
72.5%
|
|
With
hydrogen;
5% Pd(II)/C(eggshell);
In
methanol;
at 50 - 55 ℃;
under 1471.14 - 2206.72 Torr;
|
|
|
With
hydrogen;
5% Pd(II)/C(eggshell);
In
methanol;
at 50 - 55 ℃;
|
|
|
With
hydrogen;
Raney nickel;
In
methanol;
at 20 ℃;
Product distribution / selectivity;
|
|
|
{4-(benzyloxy)-3-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]phenyl}methanol;
With
hydrogen;
5%-palladium/activated carbon;
In
methanol;
at 25 - 35 ℃;
for 2h;
Autoclave;
With
methanol; sodium tetrahydroborate;
at 25 - 35 ℃;
Product distribution / selectivity;
|
|
|
With
hydrogen;
5%-palladium/activated carbon;
In
methanol;
at 25 - 30 ℃;
for 8h;
under 2206.72 - 2942.29 Torr;
|
|
|
With
palladium 10% on activated carbon; hydrogen;
In
isopropyl alcohol;
at 25 - 30 ℃;
under 2068.65 - 2585.81 Torr;
Autoclave;
|
26 g
|
|
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 20 ℃;
for 6h;
under 2250.23 - 3750.38 Torr;
Concentration;
Reagent/catalyst;
Temperature;
Time;
Inert atmosphere;
Autoclave;
Large scale;
|
5.85 kg
|
|
With
hydrogen;
5%-palladium/activated carbon;
In
methanol;
at 20 - 25 ℃;
for 6h;
under 2587.76 - 2842.78 Torr;
|
2.What is the CAS number for 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol ?
The CAS number of 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol is 207679-81-0.
More information of 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0 are:
|
CAS?Number |
207679-81-0 |
|
Density |
1.061 g/cm3 |
|
Melting Point |
68-72 °C |
|
Boiling Point |
490.721 °C at 760 mmHg |
|
Flash Point |
233.165 °C |
|
Vapor Pressure |
0mmHg at 25°C |
|
Refractive Index |
1.563 |
|
HS CODE |
2922509090 |
|
PSA |
43.70000 |
|
LogP |
4.52530 |
|
Pka |
9.61±0.48(Predicted) |
3.What are another words for 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol ?
Synonyms?for?3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0:PNU 200577;Benzenemethanol,3-[(1R)-3-[bis(1-methylethyl)- amino]-1-phenylpropyl]-4-hydroxy-;3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol;
4.What is the molecular formula of 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol?
The chemical formula of ?3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol is?C22H31NO2 which containing 22 Carbon atoms,31 Hydrogen atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol?is 341.494.
5.What is 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol (207679-81-0) used for?
3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol, also known as (R)-5-HydroxyMethyl Tolterodine, is a metabolite of Tolterodine (T535800). It is a pale yellow solid with unique chemical properties that make it a valuable compound in the pharmaceutical industry.
InChI:InChI=1/C22H31NO2/c1-16(2)23(17(3)4)13-12-20(19-8-6-5-7-9-19)21-14-18(15-24)10-11-22(21)25/h5-11,14,16-17,20,24-25H,12-13,15H2,1-4H3/t20-/m1/s1
Relevant articles related to 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol:
|
Article |
Source |
|
NOVEL (R) AND RAC 3-(2-(ALLYLOXY)-5-METHYLPHENYL)-N,N-DIISOPROPYL-3- PHENYLPROPAN-1-AMINE AND ITS USE FOR SYNTHESIS OF (R) AND RAC-2-(3- (DIISOPROPYLAMINO)-1-PHENYLPROPYL)-4-(HYDROXYMETHYL)PHENOL |
- , (2017/09/05) |
|
Iridium-Catalyzed Enantioselective Allylic Substitution of Enol Silanes from Vinylogous Esters and Amides |
Chen, Ming,Hartwig, John F. supporting information, p. 13972 - 13979 (2016/01/15) |
6.Buy 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol with the best price .
Hangzhou innopharma technology Co,.Ltd. is a quality supplier of 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0.
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