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3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol

Basic Information

  • CAS No.: 207679-81-0
  • Purity: 99%
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Details

Quality products?make an important contribution to long-term revenue and profitability. Factory supply good quality 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0 with stock

1.What is the 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol ?

A metabolite of Tolterodine, a muscarinic receptor antagonist used in the treatment of urinary incontinence.

(R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester
214601-16-8

(R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester

(R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol
207679-81-0

(R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol

Conditions
Conditions Yield
(R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester; With sodium hydroxide; In methanol; at 0 - 35 ℃; Inert atmosphere;
With lithium aluminium tetrahydride; In tetrahydrofuran; at 5 - 25 ℃; for 4h;
With water; sodium hydroxide; In tetrahydrofuran; at 0 - 5 ℃; for 3h;
98%
(R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester; With sodium hydroxide; In methanol; at 0 - 35 ℃; Inert atmosphere;
With lithium aluminium tetrahydride; In tetrahydrofuran; at 5 - 25 ℃;
With water; sodium hydroxide; In tetrahydrofuran; for 3h;
98%
(R)-(-)-3-(3-diisopropylamino-1-phenylpropyl)-4-hydroxybenzoic acid methyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 3.5h;
With ammonium chloride; In tetrahydrofuran; at -10 ℃;
95%
With sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; at 0 - 5 ℃; for 2h; Inert atmosphere;
{4-(benzyloxy)-3-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]phenyl}methanol
156755-37-2

{4-(benzyloxy)-3-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]phenyl}methanol

(R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol
207679-81-0

(R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol

Conditions
Conditions Yield
With hydrogen; 5% Pd(II)/C(eggshell); In methanol; at 50 - 55 ℃;
98%
With hydrogen; nickel; In methanol; at 20 ℃; for 4 - 5h;
96.5%
With hydrogen; In methanol; under 3000.3 - 3750.38 Torr;
72.5%
With hydrogen; 5% Pd(II)/C(eggshell); In methanol; at 50 - 55 ℃; under 1471.14 - 2206.72 Torr;
With hydrogen; 5% Pd(II)/C(eggshell); In methanol; at 50 - 55 ℃;
With hydrogen; Raney nickel; In methanol; at 20 ℃; Product distribution / selectivity;
{4-(benzyloxy)-3-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]phenyl}methanol; With hydrogen; 5%-palladium/activated carbon; In methanol; at 25 - 35 ℃; for 2h; Autoclave;
With methanol; sodium tetrahydroborate; at 25 - 35 ℃; Product distribution / selectivity;
With hydrogen; 5%-palladium/activated carbon; In methanol; at 25 - 30 ℃; for 8h; under 2206.72 - 2942.29 Torr;
With palladium 10% on activated carbon; hydrogen; In isopropyl alcohol; at 25 - 30 ℃; under 2068.65 - 2585.81 Torr; Autoclave;
26 g
With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 6h; under 2250.23 - 3750.38 Torr; Concentration; Reagent/catalyst; Temperature; Time; Inert atmosphere; Autoclave; Large scale;
5.85 kg
With hydrogen; 5%-palladium/activated carbon; In methanol; at 20 - 25 ℃; for 6h; under 2587.76 - 2842.78 Torr;

2.What is the CAS number for 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol ?

The CAS number of 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol is 207679-81-0.

More information of 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0 are:

CAS?Number

207679-81-0

Density

1.061 g/cm3

Melting Point

68-72 °C

Boiling Point

490.721 °C at 760 mmHg

Flash Point

233.165 °C

Vapor Pressure

0mmHg at 25°C

Refractive Index

1.563

HS CODE

2922509090

PSA

43.70000

LogP

4.52530

Pka

9.61±0.48(Predicted)

3.What are another words for 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol ?

Synonyms?for?3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0:PNU 200577;Benzenemethanol,3-[(1R)-3-[bis(1-methylethyl)- amino]-1-phenylpropyl]-4-hydroxy-;3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol;

4.What is the molecular formula of 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol?

The chemical formula of ?3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol is?C22H31NO2 which containing 22 Carbon atoms,31 Hydrogen atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol?is 341.494.

5.What is 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol (207679-81-0) used for?

3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol, also known as (R)-5-HydroxyMethyl Tolterodine, is a metabolite of Tolterodine (T535800). It is a pale yellow solid with unique chemical properties that make it a valuable compound in the pharmaceutical industry.

InChI:InChI=1/C22H31NO2/c1-16(2)23(17(3)4)13-12-20(19-8-6-5-7-9-19)21-14-18(15-24)10-11-22(21)25/h5-11,14,16-17,20,24-25H,12-13,15H2,1-4H3/t20-/m1/s1

Relevant articles related to 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol:

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NOVEL (R) AND RAC 3-(2-(ALLYLOXY)-5-METHYLPHENYL)-N,N-DIISOPROPYL-3- PHENYLPROPAN-1-AMINE AND ITS USE FOR SYNTHESIS OF (R) AND RAC-2-(3- (DIISOPROPYLAMINO)-1-PHENYLPROPYL)-4-(HYDROXYMETHYL)PHENOL

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6.Buy 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol with the best price .

Hangzhou innopharma technology Co,.Ltd. is a quality supplier of 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0.